MTSI
type: channel
description: La Revue Médecine Tropicale et Santé Internationale (MTSI) fait suite au Bulletin de la Société de Pathologie Exotique. MTSI est une revue en accès libre. Son contenu est disponible gratuitement pour les utilisateurs/utilisatrices ou leurs institutions qui sont libres de lire, télécharger, copier, distribuer, imprimer, rechercher ou créer des liens vers le texte intégral des articles, ou de les utiliser à toute autre fin légitime, sans demander l'autorisation préalable de l'éditeur ou des auteurs/autrices, à condition de citer correctement la source. Voir plus...
publisher: Société Francophone de Médecine Tropicale et Santé Internationale
language: fr-FR
publication name: MTSI
issn: 2778-2034
items: Schistosomiase importée chez des migrants mineurs non accompagnés à Nice (France)
items: Volontaire sain et recherche clinique au Sud : une approche communautaire
items: Étude comparative de la possession et de l'utilisation de moustiquaires imprégnées d’insecticide à longue durée d’action dans les régions de Man et Korhogo (Côte d’Ivoire)
items: Prophylaxie post-exposition contre le virus Ebola : arguments en faveur d'un élargissement du rôle des anticorps monoclonaux dans un contexte d'accès limité
items: Localisation musculaire rare d’une tuberculose mimant une tumeur cervicale : à propos d’un cas au Togo
items: Maladie vectorielle à tiques chez un randonneur en Guyane : un cas d’anaplasmose présumée
items: La mucormycose rhino-orbito-cérébrale : ne pas méconnaître l’examen direct !
items: Défi diagnostique et thérapeutique de la neuromyélite optique en Côte d’Ivoire : à propos d’un cas pédiatrique
items: Prise en charge des envenimations par morsure de serpent à l’Institut de recherche en biologie appliquée de Guinée
items: https://bulletin.societe-mtsi.fr/index.php/bspe-articles/article/view/745
items: Complications neurologiques de la dengue chez l’adulte dans les CHU de Ouagadougou au cours de l’épidémie de 2023 au Burkina Faso
items: Hypertension intracrânienne idiopathique à l'Hôpital général de référence de Niamey (Niger) : une série de huit cas
items: Brucellose humaine : trois visages d’une zoonose insidieuse
items: Le tétanos : une toxi-infection grave encore présente dans le Sud tunisien
items: https://bulletin.societe-mtsi.fr/index.php/bspe-articles/article/view/814
items: Best of du 2e congrès de la Société sénégalaise de pathologie infectieuse et tropicale (SOSEPIT), Dakar 28 au 30 avril 2025
items: Motivation et perception de l’accessibilité au vaccin par des personnes vaccinées contre la Covid-19 à Makokou au Gabon en 2021-2022
items: Yves Buisson (1948-2025)
items: Vieillir avec le VIH au Sénégal, perspectives anthropologiques pour une politique de santé publique

Schistosomiase importée chez des migrants mineurs non accompagnés à Nice (France)
type: item
description: Imported Schistosomiasis among unaccompanied minor migrants in Nice (France) Introduction. The prevalence of imported schistosomiasis among unaccompanied minor migrants (UMMs) in France is not well understood. Methodology. From December 2023 to February 2024, we screened UMMs for schistosomiasis, in addition to tuberculosis screening, at our Alpes-Maritimes Tuberculosis Control Center. We offered serological screening (Western Blot) to all UMMs from sub-Saharan Africa (SSA). If the result was positive, we offered a parasitological examination of urine and stool samples. Results. During these three months, we screened 187 UMMs from SSA. Serology was positive for 116 of them (62%). The median age was 16 years, and the sex ratio (male to female) was 6.9. Parasitological tests were performed on 58 (50%) of the 116 UMMs with positive serology results. Schistosome eggs were found in 24 of them. Fourteen UMMs had Schistosoma mansoni eggs in their stools, nine had S. haematobium eggs in their urine, and one had both S. mansoni and S. haematobium. Five UMMs had hematuria (due to S. haematobium) at the time of the study. The prevalence of schistosomiasis was at least 12.5% (24 out of 187). Discussion/Conclusion. Schistosomiasis is common among UMMs, with asymptomatic cases being the most prevalent. Schistosomiase importée chez des migrants mineurs non accompagnés à Nice (France) Introduction. La fréquence de la schistosomiase importée par les migrants mineurs non accompagnés (MNA) est mal connue en France. Méthodologie. Nous avons recherché, entre décembre 2023 et février 2024, une schistosomiase chez les MNA en plus du dépistage de la tuberculose dans notre Centre de lutte antituberculeuse des Alpes-Maritimes. Un dépistage sérologique (Western Blot) a été proposé à tous les MNA originaires d’Afrique subsaharienne (ASS). En cas de positivité, un examen parasitologique des urines et des selles a été proposé. Résultats. Au cours de ces trois mois, 187 MNA d'ASS ont été dépistés…
creator: Frédéric VANDENBOS
creator: Karine RISSO
creator: Flore PETIT
creator: Mai Ly DURANT
creator: Philippe BABE
creator: Pascal DELAUNAY
creator: Loïc SIMON
creator: Pierre MARTY
creator: Christelle POMARES
creator: Michel CARLES
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-28
publication date: 2026-01-28
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.659

Volontaire sain et recherche clinique au Sud : une approche communautaire
type: item
description: Healthy volunteers and clinical research in the South: a community-based approach Background and objectives. The participation of healthy volunteers is essential for many clinical studies. However, their situation differs from that of patients, yet they are not subject to specific ethical recommendations. Unlike patients, healthy volunteers are not seeking treatment. They are exposed to the uncertainties of a clinical trial and face with an unfavorable risk/benefit ratio. The VoIREthics charter, published by Inserm and its partners, outlines the protection principles that should protect healthy volunteers participating in clinical research. However, these principles are essentially based on Western morality and may therefore conflict with non-Western moral codes. The discussion presented here highlights the difficulties that may arise during clinical research depending on the cultural, legislative and regulatory context. Method. The VolREthics charter's recommendations were examined based on the principles of autonomy, beneficence and justice. This examination was conducted in light of literature and personal experience, to illustrate the differences in perception that may exist between Western and non-Western societies. Results and discussion. A person's place in society can limit their free will. In some societies, individual autonomy is replaced by dependence on the community. The perception of the benefit/risk balance must relate to the scale of the community, not the individual. In traditional medicine, therapeutic efficacy does not result from treatment alone, and therapeutic risk is not understood in the same way as in Western medicine. Furthermore, healthy volunteers must reflect the diversity of the population. If they are selected through a community consensus, the inclusion criteria cannot escape the investigator's or sponsor's control. Conclusion. The principles set out in the VolREthics charter must be contextualized to ensure acceptance by the study st…
creator: Jean-Philippe CHIPPAUX
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-02-23
publication date: 2026-02-23
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.823

Étude comparative de la possession et de l'utilisation de moustiquaires imprégnées d’insecticide à longue durée d’action dans les régions de Man et Korhogo (Côte d’Ivoire)
type: item
description: Comparative study of the ownership and use of long-lasting insecticide-treated mosquito nets in the Man and Korhogo regions (Côte d’Ivoire) Rationale. Malaria remains a significant public health concern in sub-Saharan Africa. To prevent the transmission of the disease, long-lasting insecticide-treated mosquito nets (LLINs) have been periodically distributed in Côte d'Ivoire. This study aims to determine the availability and utilization rate of LLINs in two National Malaria Control Program (NMCP) sentinel sites. A sentinel site is a location selected by the NMCP to ensure continuous, standardized malaria epidemiological, parasitological, and entomological surveillance. Materials and methods. A descriptive, cross-sectional survey was conducted from January to March of 2019. Two hundred heads of households were surveyed in urban (Camp Sea and Logokaha) and rural (Kassiapleu and Kaforo) areas in Man and Korhogo. These two sites have different malaria epidemiological contexts. Data were collected using questionnaires administered to household heads or their representatives at home. The questionnaires gathered information on the household heads' sociodemographic characteristics, their perceptions and knowledge of malaria risk, and their possession of and experience with using LLINs within their households. Results. In at least 70% of cases, households associated malaria transmission with mosquito bites. Additionally, 87% of respondents reported owning at least one LLIN, and 84% said they had used it the previous night. This usage rate exceeds the 80% recommended by the World Health Organization. Conclusion. This study shows that the surveyed populations have a good understanding of LLINs to protect themselves, regardless of the transmission context. However, some results suggest that health authorities could take measures to improve LLIN use among these populations. Étude comparative de la possession et de l'utilisation de moustiquaires imprégnées d’insecticide à longue d…
creator: Konan Fabrice ASSOUHO
creator: Florence FOURNET
creator: Konan Rodolphe Mardoché AZONGNIBO
creator: Akré Maurice ADJA
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-03-25
publication date: 2026-03-25
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.743

Prophylaxie post-exposition contre le virus Ebola : arguments en faveur d'un élargissement du rôle des anticorps monoclonaux dans un contexte d'accès limité
type: item
description: Post-exposure prophylaxis against Ebola virus: arguments for expanding the role of monoclonal antibodies in a context of limited access Introduction and methods. While Ebola virus disease (EVD) remains a major threat, recent advances have led to the approval of several medical products, in particular the rVSV?G-ZEBOV-GP vaccine (Ervebo) and two monoclonal antibody treatments, mAb114 (Ebanga) and REGN-EB3 (Inmazeb). However, their use in post-exposure prophylaxis (PEP) remains poorly documented. Our narrative review of the literature and guidelines aims to assess the potential of the rVSV?G-ZEBOV-GP vaccine and monoclonal antibodies mAb114 and REGN-EB3 for PEP following high-risk exposure. Results. Very few studies have been conducted specifically to determine the efficacy of vaccines or monoclonal antibodies as PEP. Data from animals and humans suggest that the rVSV?G-ZEBOV-GP vaccine offers only limited protection as PEP, although it may reduce the severity of EVD if it occurs. None of the 34 individuals who have received the vaccine as PEP to date have developed EVD. A retrospective case-control study suggests an efficacy of only 16% against the occurrence of EVD when the vaccine is administered during a period compatible with PEP. In contrast, the monoclonal antibodies mAb114 and REGN-EB3, due to their immediate action through passive immunisation, appear to confer higher protection against the onset of EVD after high-risk exposure, with 100% survival in animal models, although human clinical data remain scarce with only 23 cases of use reported in PEP and no occurrence of EVD. Discussion and conclusion. Access to monoclonal antibodies for community members following high-risk exposure should be ensured, while optimising risk assessment criteria. Further research, particularly on the interaction between vaccination and antibody administration, is essential to determine the most effective PEP strategies. Finally, an emergency stockpile of monoclonal antibodies and…
creator: Julien POTET
creator: Ismael ADJAHO
creator: Kerry DIERBERG
creator: Armand SPRECHER
creator: Rebecca Marie COULBORN
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-03-31
publication date: 2026-03-31
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.835

Localisation musculaire rare d’une tuberculose mimant une tumeur cervicale : à propos d’un cas au Togo
type: item
description: Rare muscular localization of tuberculosis mimicking a cervical tumor: a case report from Togo Objective. The detection of tuberculosis in an apparently isolated location, such as the sternocleidomastoid muscle, is exceptional. It can be mistaken for a cervical tumor. This report presents a case with its diagnostic and therapeutic particularities. Observation. An immunocompetent patient presented with right anterolateral cervical swelling, which was suggestive of a thyroid tumor. Paraclinical investigations revealed tuberculosis of the right sternocleidomastoid muscle and a latent homolateral pulmonary focus. The patient responded well to medical treatment. Conclusion. Muscular tuberculosis in the cervical region can mimic a cervical tumor. Localisation musculaire rare d’une tuberculose mimant une tumeur cervicale?: à propos d’un cas au Togo Objectif. La révélation d’une tuberculose par une localisation apparemment isolée dans le muscle sternocléidomastoïdien est exceptionnelle. Elle peut prêter à confusion avec une tumeur cervicale. Nous rapportons un cas avec ses particularités diagnostiques et thérapeutiques. Observation. Patient immunocompétent présentant une tuméfaction cervicale antérolatérale droite faisant suspecter une tumeur de la thyroïde. Les explorations paracliniques ont permis de découvrir une tuberculose du muscle sternocléidomastoïdien droit et un foyer pulmonaire latent homolatéral. L’évolution sous traitement médical a été favorable. Conclusion. La tuberculose musculaire au niveau cervical peut mimer une tumeur cervicale.
creator: Essobozou Plaodezina PEGBESSOU
creator: Winga FOMA
creator: Gérémie ANANIDJIN
creator: Essobiziou AMANA
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-03-18
publication date: 2026-03-18
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.831

Maladie vectorielle à tiques chez un randonneur en Guyane : un cas d’anaplasmose présumée
type: item
description: Tick-borne disease in a backpacker in French Guiana: one case of presumed anaplasmosis Introduction. New species of Borrelia, Rickettsia, and Anaplasma have recently been detected in ticks in French Guiana. Additionally, a new species of Anaplasma was discovered in a human. Specific genovariants of Anaplasma and Ehrlichia have also been identified in the Amazonian forest of French Guiana, indicating a specific sylvatic cycle. Case presentation. We present the case of a patient who experienced fever, myalgia, rash, and inoculation eschars following dozens of tick bites while hiking in the Amazon rainforest. Laboratory results showed lymphopenia, neutrophilia, hepatic cytolysis and cholestasis, and a C-reactive protein level of 78 mg/L. Serology tests for HIV, hepatitis A, B, C, and E; cytomegalovirus; syphilis; and Q fever were negative. NS1 antigen, dengue, and leptospirosis PCR tests were also negative. A skin biopsy of an ulcerated papule on the leg revealed a polymorphic dermal inflammatory infiltrate with intramacrophagic Gram-negative bacilli. Blood PCR for Anaplasma phagocytophilum, Borrelia, Rickettsia, and Babesia were negative. Serology tests were negative for Rickettsia conorii and R. typhi, but positive for A. phagocytophilum, with weakly positive IgM and positive IgG. Serological results were confirmed by controlled sample. The patient improved with doxycycline treatment. Discussion and conclusion. Novel species of Anaplasma and Ehrlichia have been detected in the Amazon rainforest of French Guiana. These novel genovariants differ from other species in the Northern Hemisphere and are difficult to diagnose with molecular tools not designed to detect pathogens differing from known species. While not proven by molecular biology, this case may represent an anaplasmosis or another infection from the Rickettsiales group. This highlights that little is known about the potential for tick-borne diseases in French Guiana. In this context, recommendations for vecto…
creator: Morgane BOURNE-WATRIN
creator: Kinan DRAK ALSIBAI
creator: Olivier DURON
creator: Justin DESTOOP
creator: Maylis DOUINE
creator: Loïc EPELBOIN
creator: Pierre COUPPIÉ
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-03-13
publication date: 2026-03-13
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.826

La mucormycose rhino-orbito-cérébrale : ne pas méconnaître l’examen direct !
type: item
description: Rhino-orbito-cerebral mucormycosis: don't overlook direct examination! Introduction. Rhino-orbito-cerebral mucormycosis is the most common clinical form of mucormycosis. The most common underlying condition associated with this form is diabetes, especially in cases of glycemic imbalance. Observation. This report concerns a 13-year-old girl with type 1 diabetes who was admitted for ketoacidosis. Clinical and radiological examinations revealed progressive orbital cellulitis (Chandler stage II, then V). Despite initiating antibiotic and antifungal treatment, there was no improvement. Surgery was performed to remove necrotic tissue, and mycological and anatomopathological examinations confirmed the diagnosis of mucormycosis. The patient was successfully treated with liposomal amphotericin B for two months. Discussion/Conclusion. Although this infection is rare, it should always be suspected in cases of facial cellulitis, especially in patients with poorly controlled diabetes, to ensure rapid and effective treatment. La mucormycose rhino-orbito-cérébrale : ne pas méconnaître l’examen direct ! Introduction. La mucormycose rhino-orbito-cérébrale est la forme clinique la plus fréquente des mucormycoses. Le diabète représente la pathologie sous-jacente la plus souvent en cause dans cette forme, surtout en cas de déséquilibre glycémique. Observation. Le cas rapporté concerne une adolescente de 13 ans, diabétique de type 1, admise pour une décompensation acidocétosique. Les examens cliniques et radiologiques ont révélé une cellulite orbitaire évolutive (stade II puis V de Chandler). Un traitement antibiotique et antifongique a été instauré mais sans amélioration. Une intervention chirurgicale a permis de retirer un tissu nécrosé dont les examens mycologique et anatomopathologique ont confirmé le diagnostic de mucormycose. La patiente a été traitée avec succès par amphotéricine B liposomale pendant deux mois. Discussion/Conclusion. Bien que peu fréquente, cette infection doit ê…
creator: Imane ZOUAOUI
creator: Yassine BAY BAY
creator: Houda DOSS-BENNANI
creator: Sarra AOUFI
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-20
publication date: 2026-01-20
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.702

Défi diagnostique et thérapeutique de la neuromyélite optique en Côte d’Ivoire : à propos d’un cas pédiatrique
type: item
description: Diagnostic and therapeutic challenges of neuromyelitis optica in Côte d'Ivoire: a pediatric case report Introduction. Neuromyelitis optica (NMO) is an inflammatory and demyelinating disease of the central nervous system (CNS) that typically progresses in episodes. The average age of onset is around 40 years old, though there are also pediatric forms. We present our first pediatric case and discuss its unique features. Clinical observation. An 8-year-old child was hospitalized in June 2023 due to motor deficits in all four limbs. In November 2021, she presented with a binocular decrease in visual acuity, followed by partial recovery. Eleven months later, she experienced a second, more severe episode without recovery. In May 2023, she presented with uncontrollable vomiting and a mild motor deficit in all four limbs. By June 2023, she reported significant asthenia, severe facial itching, and worsening motor deficits. Her EDSS score was estimated at 8. Ophthalmologically, she had an absence of light perception and optic atrophy on fundus examination. Testing confirmed seropositive NMO. Following corticosteroid therapy, she showed clinical improvement with an EDSS score of 5.5. Following a relapse on azathioprine, her condition remained stable on rituximab. Discussion. NMO accounts for 3 to 5% of all NMO cases in children and is often underdiagnosed. There is clinical and radiological heterogeneity in pediatric NMO. Misleading forms, such as area prostema syndrome (which is quite common in children), should not be overlooked. Basic treatments are based on immunosuppressants. Conclusion. NMO is a rare and little-known condition in sub-Saharan Africa, with flare-ups representing genuine therapeutic emergencies. Défi diagnostique et thérapeutique de la neuromyélite optique en Côte d’Ivoire : à propos d’un cas pédiatrique Introduction. La neuromyélite optique (NMO) est une pathologie inflammatoire, démyélinisante du système nerveux central (SNC) évoluant généralement par pou…
creator: Claude Valéry Cédric Aka KADJO
creator: Constance YAPO-EHOUNOUD
creator: Reine Prisca AGBOHOUN
creator: Arlette Désirée AKA
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-13
publication date: 2026-01-13
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.707

Prise en charge des envenimations par morsure de serpent à l’Institut de recherche en biologie appliquée de Guinée
type: item
description: Treatment of snakebites at the Guinea Institute for Applied Biology Research Objectives. This study aims to present the epidemiological and clinical characteristics of snakebites treated in Kindia, Guinea, between 2015 and 2019. Materials and methods. We conducted a retrospective descriptive study covering the period from January 2015 to December 2019. The study included all patient records for envenomation from snakebites at the Institut de Recherche en Biologie Appliquée de Guinée in Kindia. Results. A total of 1,420 snakebites were recorded, including 1,008 envenomations (male-to-female ratio = 1.2), over a 60-month period. Most patients (76.9%) came from rural areas and were primarily involved in agriculture and livestock farming. In 85.4% of cases, the bites were to the lower limbs. Viper syndrome was predominant, and 98.5% of patients received antivenom with a 95.9% cure rate. Conclusion. The results of this study demonstrate that snakebite envenomation are common and have a 2.5% case-fatality rate. These results suggest the need for greater consideration of snakebites in Guinea's health policy. Prise en charge des envenimations par morsure de serpent à l’Institut de recherche en biologie appliquée de Guinée Objectifs. Le but de cette étude est de présenter les caractéristiques épidémiologiques et cliniques des envenimations par morsure de serpent traitées de 2015 à 2019 à Kindia, en Guinée. Matériel et méthodes. Nous avons réalisé une étude rétrospective descriptive d’une période de 5 ans (janvier 2015 à décembre 2019), incluant tous les dossiers de patients admis pour envenimation par morsure de serpent à l’Institut de recherche en biologie appliquée de Guinée, à Kindia. Résultats. Il a été enregistré 1 420 cas de morsure dont 1 008 envenimations (sex-ratio H/F = 1,2) en 60 mois. Les patients provenaient majoritairement du milieu rural (76,9 %) et pratiquaient principalement l’agriculture et l’élevage. Les morsures siégeaient aux membres inférieurs dans 85,4…
creator: Ousmane BALDÉ
creator: Mamadou Alpha BALDÉ
creator: Mamadou Cellou BALDÉ
creator: Mohamed Ciré DIALLO
creator: Mohamed Sahar TRAORÉ
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-26
publication date: 2026-01-26
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.803

https://bulletin.societe-mtsi.fr/index.php/bspe-articles/article/view/745
type: item
title: Évaluation de l’efficacité et de la tolérance de l’acide tranexamique associé à l’antivenin InoserpTM PAN-AFRICA dans le traitement du syndrome hémorragique au cours de l’envenimation par Echis ocellatus au Bénin
description: Evaluation of the Efficacy and Tolerance of Tranexamic Acid Combined with InoserpTM PAN-AFRICA Antivenom in the Treatment of Hemorrhagic Syndrome during Envenomation by Echis ocellatus in Benin Introduction. Hemorrhagic syndrome accounts for a significant proportion of the mortality and morbidity associated with snakebites in sub-Saharan Africa. Hyperfibrinolysis, which has been reported in some cases, suggests the potential benefit of antifibrinolytics; however, these have been little studied in this context. This study aimed to evaluate the effectiveness of combining tranexamic acid and antivenom in treating hemorrhagic syndrome and coagulopathy associated with Echis ocellatus (West African Carpet Viper) envenomation. Materials and methods. Patients presenting with hemorrhagic syndrome due to envenomation were prospectively included at the Saint Jean de Dieu Hospital in Tanguiéta, Benin. Patients were randomized into two groups: one receiving antivenom and tranexamic acid (SAV + AT) and one receiving only antivenom (SAV). All patients received two vials of InoserpTM PAN-AFRICA antivenom upon admission. The SAV + AT group received 1 g of tranexamic acid over 30 minutes, followed by an additional 1 g over 8 hours. The occurrence of bleeding and the results of blood coagulation tests (whole blood clotting test or WBCT) were recorded at 2, 4, 6, 8, 12, 24, 48, and 72 hours after the initial antivenom administration. Antivenom administration was repeated if bleeding occurred at any of these times. The INR (International Normalized Ratio) was measured at six and twelve hours. Tolerance was assessed at 1, 2, 4, 6, 8, 12, 24, 48, and 72 hours. Plasma creatinine was measured at 24 and 72 hours. Results. Twenty-five patients were included: Twelve patients were in the SAV + AT group, and thirteen patients were in the SAV group. Six patients in the SAV + AT group and five patients in the SAV group experienced persistent or recurrent bleeding (p = 0.695). There was no signific…
creator: Sébastien LARRÉCHÉ
creator: Noé SODJINOU
creator: Naryanan TOURITA
creator: Seidou Alassane OUOROU
creator: Éric GANHOUINGNON
creator: Édith ALOUKOUTOU LAYO
creator: Achille MASSOUGBODJI
creator: Jean-Philippe CHIPPAUX
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-03-15
publication date: 2026-03-15
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.745

Complications neurologiques de la dengue chez l’adulte dans les CHU de Ouagadougou au cours de l’épidémie de 2023 au Burkina Faso
type: item
description: Neurological complications of dengue fever in adults at Ouagadougou university hospitals during the 2023 epidemic in Burkina Faso Introduction. The most recent dengue epidemic in Burkina Faso in 2023 resulted in the highest morbidity and mortality rates in Africa. Neurological complications of dengue are associated with high mortality rates. This study investigated these complications in adults hospitalized at the Ouagadougou University Hospital during the 2023 dengue epidemic in Burkina Faso. Patients and methods. This cross-sectional, retrospective, descriptive, and analytical study examined confirmed cases of dengue fever in adults hospitalized from January 1 to December 31, 2023, at the University Hospitals of Ouagadougou. We analyzed the frequency of dengue fever-related neurological complications and the sociodemographic, clinical, paraclinical, and intra-hospital data of these patients. A bivariate analysis, followed by a multivariate study using multiple logistic regression, identified factors associated with in-hospital mortality. Results. A total of 1,057 patients were hospitalized with dengue fever in Ouagadougou's university hospitals during the epidemic period. Of these patients, 116 (11%) presented with neurological complications. The mean age of these patients was 47.6 years, and 51.7% were female. The most frequently found neurological clinical signs were impaired consciousness (84.5%), epileptic seizures (20.7%), and psycho-behavioral disorders (14.6%). The neurological complications encountered were encephalopathies (7.8%), probably dengue-related encephalitis (0.8%), strokes (0.7%), and Guillain-Barré syndrome (0.1%). The in-hospital mortality rate was 69% (80 patients), and acute renal failure was the only independent factor associated with it (OR = 3.49; p = 0.02). Conclusion. In Burkina Faso, the neurological complications of dengue are primarily multifactorial encephalopathies, which are associated with a high mortality rate. Screening patient…
creator: Djingri Labodi LOMPO
creator: Sylvie KAGAMBEGA D
creator: Souleymane OUATTARA
creator: Alassane ZOUNGRANA
creator: Melody Zeinab GNAMPA
creator: Fabienne Yabtouta KERE
creator: Christian NAPON
creator: Athanase MILLOGO
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-07
publication date: 2026-01-07
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.794

Hypertension intracrânienne idiopathique à l'Hôpital général de référence de Niamey (Niger) : une série de huit cas
type: item
description: Idiopathic intracranial hypertension at the Niamey General Reference Hospital (Niger): a series of eight cases Introduction. Idiopathic intracranial hypertension (IIH) typically affects young, obese women. This condition is rarely described in sub-Saharan African countries. This study reports on the clinical and evolutionary characteristics of patients diagnosed with IIH in Niamey, Niger. Materials and methods. We retrospectively analyzed observations of eight patients diagnosed with IIH in the neurology department of the Niamey General Reference Hospital between June 1, 2021, and May 31, 2023. Results. All patients presented with headaches and subacute bilateral visual acuity loss. Their median age was 29.5 years. Their median body mass index (BMI) was 30.75 kg/m² (interquartile range [IQR]: 26–32). Fundus examinations revealed bilateral papilledema in all patients. The median cerebrospinal fluid pressure upon opening was 30 cm H?O (interquartile range [IQR]: 28.35 to 35). Brain and vascular imaging were normal. All patients completely recovered their vision and experienced normalization of the fundus under acetazolamide treatment, after which treatment was discontinued. Six months after discontinuing acetazolamide, one patient relapsed, necessitating the reintroduction of long-term treatment. Conclusion. Intracranial hypertension (IIH) is a rare neurological disorder that usually affects young, obese women, but its incidence is increasing due to the obesity epidemic. This is the first series of Nigerien cases of IIH. Hypertension intracrânienne idiopathique à l'Hôpital général de référence de Niamey (Niger) : une série de huit cas Introduction. L'hypertension intracrânienne idiopathique (HII) survient généralement chez les femmes jeunes et obèses. L'HII est une pathologie rarement décrite dans les pays d'Afrique subsaharienne. Nous rapportons les caractéristiques cliniques et évolutives de patientes nigériennes diagnostiquées avec une HII à Niamey (Niger). Matérie…
creator: Zakaria MAMADOU
creator: Souleymane MAHAMADOU-ANGO
creator: Moussa TOUDOU-DAOUDA
creator: Inoussa DAOUDA BAKO
creator: Moussa ATTTAHER
creator: Haoua SIDIBE
creator: Amadou ABDOU-BACHAROU
creator: Fataoulaye SOUMANA
creator: Éric ADEHOSSI
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-13
publication date: 2026-01-13
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.692

Brucellose humaine : trois visages d’une zoonose insidieuse
type: item
description: Human brucellosis: three faces of an insidious zoonosis Introduction. Human brucellosis is a prevalent zoonotic disease in Tunisia, especially in rural areas with significant livestock activity. The disease can manifest as localized or systemic forms, and its clinical presentation is highly polymorphic. Here, we present three cases that illustrate this clinical diversity. Observation 1. A 69-year-old diabetic man living in a rural area presented with a painful cervical swelling. Computed tomography revealed cervical cellulitis and pyomyositis. Culture of the pus from the cellulitis yielded positive results for Brucella spp., and the patient was treated with doxycycline and rifampicin for six weeks, along with surgical drainage. The outcome was favorable. Observation 2. A 48-year-old male intravenous drug user was hospitalized due to a prolonged fever associated with a heart murmur. Echocardiography revealed tricuspid vegetation measuring 34×24 mm and moderate tricuspid regurgitation. A blood culture revealed Brucella spp., and treatment consisted of a combination of antibiotics, including doxycycline and rifampicin, as well as valve surgery. The outcome was favorable with this combined treatment. Observation 3. A 50-year-old cirrhotic patient was admitted with febrile hepatic encephalopathy that did not improve with empirical antibiotic therapy. Blood cultures isolated Brucella spp., and appropriate treatment led to a marked clinical improvement. Conclusion. Human brucellosis presents with a variety of clinical manifestations that complicate its diagnosis. In Tunisia, clinical vigilance is essential for the early diagnosis and appropriate management of the disease, particularly in at-risk patients. Prospective studies are needed to better define treatment protocols, especially for complex forms of the disease. Brucellose humaine : trois visages d’une zoonose insidieuse Introduction. La brucellose humaine est une zoonose fréquente en Tunisie, particulièrement dans le…
creator: Manel ENNACEUR
creator: Khaoula SOULI
creator: Sonia CHOUAIEB
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-02-19
publication date: 2026-02-19
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.821

Le tétanos : une toxi-infection grave encore présente dans le Sud tunisien
type: item
description: Tetanus: a serious toxic infection still present in southern Tunisia Introduction. Although there has been a significant decline in tetanus cases thanks to vaccination, it remains a public health problem, particularly in developing countries. The epidemiology of tetanus in Tunisia has not been updated in over 20 years. Our study aims to examine the epidemiological, clinical, paraclinical, therapeutic, and evolutionary characteristics of patients with severe tetanus in intensive care. Materials and methods. This retrospective study was conducted in the multi-purpose intensive care unit at Habib Bourguiba University Hospital in Sfax. It spanned 19 years. We included all suspected cases of severe tetanus according to the WHO definition, which includes trismus and/or generalized contractures and/or paroxysms in an unvaccinated or poorly vaccinated patient. Results. Sixteen patients were included. The frequency was 0.84 cases per year, and the patients' average age was 61.6 ± 10.1 years. There was a predominance of males, with a sex ratio of 2.2. Half of the patients were manual laborers who worked in rural areas during the hot seasons. The most common symptom was a skin wound with traumatic inoculation in the lower limbs (10 patients), with 14 patients presenting with this symptom. None of the patients had been vaccinated. According to Ablett's classification, half of our patients had severe or very severe forms of the disease. All patients had generalized tetanus with trismus, neck stiffness, dysphagia, and generalized muscle contractures. Thirteen patients experienced paroxysms, and fourteen had dysautonomic disorders, the most common of which were tachycardia episodes (six patients). Fifteen patients required mechanical ventilation, with an average duration of 24.9 ± 15.8 days. The total length of stay was 29.7 ± 16.5 days, and five patients died during hospitalization. Conclusion. Despite advances in intensive care in Tunisia, tetanus remains a serious disease with …
creator: Sabrine BRADAI
creator: Slim BOUAZIZ
creator: Amina HADDED
creator: Najeh BACCOUCH
creator: Mabrouk BAHLOUL
creator: Chokri BEN HAMIDA
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-24
publication date: 2026-01-24
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.802

https://bulletin.societe-mtsi.fr/index.php/bspe-articles/article/view/814
type: item
title: Proposition d’algorithme décisionnel lors de discordances entre épreuves globulaire (Beth-Vincent) et sérique (Simonin) dans le groupage ABO au laboratoire d’immunologie du CHU de Bouaké (Côte d’Ivoire)
description: A proposed decision-making algorithm for discrepancies between red blood cell (Beth-Vincent) and serum (Simonin) tests in ABO blood typing at the Immunology Laboratory of Bouaké University Hospital (Côte d’Ivoire) Introduction. ABO blood typing relies on two complementary tests: the red blood cell test (Beth-Vincent) and the serum test (Simonin-Michon). Concordance between these tests is essential for transfusion safety. Persistent discrepancies, though rare, are critical and require thorough investigation. Methods and case presentation. Thirteen patients (aged 6-73) were examined for persistent ABO discordance. We performed parallel Beth-Vincent and Simonin tests. In the event of discordance, we triple washed the red blood cells in saline solution. Auto-, allo-, and ABO controls were systematically performed. The clinical contexts included trauma, anemia, and preoperative and prenatal assessments. Most patients had no history of previous transfusion. Most cases presented a positive auto control, suggesting the presence of autoantibodies, and/or a positive AB control, indicating polyagglutinability. Discrepancies mainly concerned conflicts between direct and inverse ABO phenotypes (AB/O, A/O, and B/O). These results demonstrate the value of controls in guiding diagnosis and the need for complementary approaches. Conclusion. This series illustrates the decision-making algorithm proposed for cases with persistent discrepancies between red blood cell and serum tests during ABO blood typing. Proposition d’algorithme décisionnel lors de discordances entre épreuves globulaire (Beth-Vincent) et sérique (Simonin) dans le groupage ABO au laboratoire d’immunologie du CHU de Bouaké (Côte d’Ivoire) Introduction. Le groupage sanguin ABO repose sur deux épreuves complémentaires : l’épreuve globulaire (Beth-Vincent) et l’épreuve sérique (Simonin-Michon). La concordance entre ces tests est essentielle pour la sécurité transfusionnelle. Les discordances persistantes, rares mais crit…
creator: Lasme Roselle Charline MEMEL
creator: Adjoumanvoule Honoré ADOU
creator: Aya Ursule Aniela ASSI-SAHOUIN
creator: Hebert Gautier KOYA
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-02-05
publication date: 2026-02-05
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.814

Best of du 2e congrès de la Société sénégalaise de pathologie infectieuse et tropicale (SOSEPIT), Dakar 28 au 30 avril 2025
type: item
description: Résumé du congrès et du précongrès Aminata MASSALY (1), Agbogbenkou Tevi Dela Dem LAWSON (2), Moustapha DIOP (3)), Maimouna SIDIBE (2), Aboubacar Sadikh BADIANE (1), Ndeye Maguette FALL (1), Daouda THIOUB (1), Kourro BOUSSO (4), Aminata THIAM (5), Alassane DIEYE (6), Kalilou DIALLO (7), Viviane Marie Pierre CISSE (1), Daye KA (1), Ndeye Aissatou LAKHE1), Khardiata DIALLO-MBAYE (1), Pape Samba BA (3), Ndèye Fatou Ngom GUEYE (8), Louise FORTES (9), Noël Magloire MANGA (7), Sylvie Audrey DIOP (2), Khadidiatou Maïmouna BA FALL (10), Moussa SEYDI (1), Loïc EPELBOIN (11), Ndeye Mery DIA BADIANE (12) Pré-congrès, CHU Fann, Dakar, 28 avril 2025 Thème : Prévention des infections associées aux soins (IAS) La journée précongrès du 2e congrès de la SOSEPIT a été consacrée à la prévention des infections associées aux soins, enjeu majeur de sécurité des patients en Afrique. Après l’accueil des participants et l’ouverture officielle par les organisateurs, les échanges ont débuté par une session introductive sur les concepts clés des IAS, animée par les Prs Louise Fortes et Aissatou Lakhe. Cette session a été suivie d’un atelier pratique sur l’hygiène des mains et le port de gants, illustrant les gestes barrières essentiels. La matinée s’est poursuivie avec un second atelier sur les précautions complémentaires (contact, air, gouttelettes), présenté par les Drs Sokhna Daffe et Tracie Youbong, axé sur l’adaptation des mesures préventives aux risques spécifiques. Un troisième atelier, animé par le Pr Daye Ka et Mme Aïssa Sow Barry, a abordé la prévention des IAS liées aux dispositifs médicaux, avec un focus sur les bonnes pratiques de pose, d’entretien et de retrait. La clôture du précongrès a permis de synthétiser les messages clés et de remettre les certificats de participation à 169 agents de santé. Cette journée interactive, combinant apports théoriques et démonstrations pratiques, a offert aux participants un socle commun pour renforcer la lutte contre les IAS dans leurs structur…
creator: SOSEPIT (Société sénégalaise de pathologie infectieuse et tropicale)
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-23
publication date: 2026-01-23
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.801

Motivation et perception de l’accessibilité au vaccin par des personnes vaccinées contre la Covid-19 à Makokou au Gabon en 2021-2022
type: item
description: Motivation and perception of vaccine accessibility among people vaccinated against COVID-19 in Makokou, Gabon, in 2021–2022 Introduction. Vaccination is one of the responses to the ongoing global COVID-19 pandemic. However, it has also sparked controversy, hesitation, and infodemics worldwide. Gabon began vaccinating its population in July 2021. Our study aims to describe the motivations, knowledge, and levels of acceptance of volunteers. Methods. We conducted a descriptive, cross-sectional, "knowledge, attitudes, and practices" study from May 2021 to January 2022 (eight months) at the only COVID-19 vaccination center in Makokou, in Gabon's Eastern Health Region. Volunteers were included during the vaccination process and responded to a questionnaire during a face-to-face interview. We studied their sociodemographic profile, knowledge of the disease and the vaccine, and perceptions and experiences of accessibility. Results. A total of 323 people between 18 and 71 years old, were included in the study. Subjects aged 30 to 40 years old represented 39% (120 subjects) of those included. The sex ratio was 2.7. Eighty-seven percent of participants were of Gabonese nationality, and the median length of stay in the city of Makokou was six years (IQR: 2-15). The most represented professions were health workers (18%, or 54 people), followed by defense and security forces (16%, or 48 people), who were the main targets of the program. Forty-three percent (129) of participants reported being influenced in their decision to get vaccinated. Globally, 72.6% (220) thought that vaccination was a constraint, either for health reasons (58.2%) or for greater freedom of movement (49.5%). The main sources of information were the media (237, or 83%) and medical personnel (168, or 57%). Motivation was associated with compulsion (OR = 2.2), knowledge of certain symptoms (OR = 0.4), perception of the disease as serious (OR = 0.2), and positive media influence (OR = 0.4). Accessibility was ass…
creator: Ulrick Jolhy BISVIGOU
creator: Euloge IBINGA
creator: Cédric Noël MINKO
creator: Sydney MAGHENDJI NZONDO
creator: Edgard Brice NGOUNGOU
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-01-29
publication date: 2026-01-29
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.514

Yves Buisson (1948-2025)
type: item
description: .
creator: Jean-Paul BOUTIN
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-03-14
publication date: 2026-03-14
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.827

Vieillir avec le VIH au Sénégal, perspectives anthropologiques pour une politique de santé publique
type: item
description: Growing old with HIV in Senegal: an anthropological perspective for a public health policy Introduction. Thanks to the effectiveness of antiretroviral treatment (ART), more and more people in Africa are aging with HIV. In Senegal, 34% of people living with HIV (PLHIV) who received ART were 50 years of age or older in 2022. As people age, their medical, psychological, and social needs gradually change and increase. This article presents the results of an anthropological study that aimed to describe and analyze the living conditions and care of PLHIV aged 70 and over in urban areas, in relation to the health and social context. Materials and methods. The ethnographic study was conducted from 2022 to 2023 in the Dakar metropolitan area. The study focused on 31 older people living with HIV (OPLHIV), including 14 women, with an average age of 72 (maximum age 90). The median duration of ART was 16 years (maximum: 22 years). Six family caregivers, four community mediators, one nurse, and five doctors (including a geriatrician) were also interviewed, as well as the main national officials responsible for the fight against AIDS. Results. The OPLHIV who were interviewed reported habituation to HIV and demonstrated excellent adherence to ART. However, persistent social stigma surrounding HIV continues to affect their daily lives, leading to various forms of self-exclusion and strategies to keep their illness secret. Medically, they are all in virological remission; however, they face multiple comorbidities and functional disabilities that lead to increased healthcare costs. Economic insecurity and inadequate social protection systems lead to increased dependence on loved ones. Families are the main providers of care. However, the attention given to the elderly depends on the nature and quality of the relationships they have built throughout their lives. Conclusion. This research contributes to anthropology's analysis of healthcare systems and their capacity to care for specifi…
creator: Bernard TAVERNE
creator: Gabrièle LABORDE-BALEN
creator: Seynabou DIOP
creator: Catherine FALL
creator: Marcel Ndiana NDIAYE
creator: Pierre Thiouthy SARR
creator: Khoudia SOW
rights: © MTSI 2026 https://creativecommons.org/licenses/by/4.0
license: https://creativecommons.org/licenses/by/4.0
date: 2026-02-27
publication date: 2026-02-27
volume: 6
number: 1
doi: 10.48327/mtsi.v6i1.2026.769